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Beilstein J. Org. Chem. 2014, 10, 2414–2420, doi:10.3762/bjoc.10.251
Graphical Abstract
Scheme 1: The structure of δ-aminolevulinic acid (1), a precursor in cellular biosynthesis of protoporphyrin ...
Scheme 2: Synthesis of conjugate 2 i) Br2, Ph3P, DMF, 75–80 °C, 93% according to [16]; ii) 2-hydroxyethylamine, 8...
Figure 1: 13C NMR spectrum of 2 (D2O, 125 MHz) with assignment of the peaks.
Figure 2: Representative confocal microscopy images of MCF7 cells incubated with 1 mM 2 (a, b and c), and 1 m...
Figure 3: Representative confocal fluorescence microscopy images of MCF7 cells after incubation with a soluti...